Next-Generation DNA Sequencing Informatics, Stuart M. Brown

Next-generation DNA sequencing (NGS) technology has revolutionized biomedical research, making complete genome sequencing an affordable and frequently used tool for a wide variety of research applications. Bioinformatics methods to support DNA sequencing have become a critical bottleneck for many researchers and organizations wishing to make use of NGS technology. This book provides a thorough introduction to the necessary informatics methods and tools for operating NGS instruments and analyzing NGS data. The book also provides extensive reference to best-practice bioinformatic methods for the most commonly used NGS technologies and applications. The book also includes reference to, and guidance, on the setup and use of essential software for NGS data analysis. This is the first book of its kind to address the informatics needs of scientists who wish to take advantage of the explosion of research opportunities offered by new DNA sequencing technologies.

Here researchers at New York University's Langone Medical Center provide an overview of many core types of next-generation sequencing projects, discuss methods embodied in popular software, and describe in detail their own best practice workflows. The information and advice could help both bioinformaticians implementing their own data and analysis method, and laboratories and clinical investigators planning to use next-generation sequencing methods for research.

Product Details :
Hardcover: 256 pages
Publisher: Cold Spring Harbor Laboratory Press (January 1, 2013)
Language: English
ISBN-10: 1936113872
ISBN-13: 978-1936113873
Product Dimensions: 10.3 x 7.3 x 0.9 inches

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Biochemistry (Lippincott's Illustrated Reviews Series) 5th Edition, Richard A. Harvey PhD

Thoroughly updated for its Fifth Edition, Lippincott's Illustrated Reviews: Biochemistry enables students to quickly review and assimilate large amounts of complex information through powerful visual resources essential to mastery of difficult biochemical concepts. Its signature outline format, full-color illustrations, end-of-chapter summaries, and USMLE-style review questions make it one of the most user-friendly books in the field. New features include expanded coverage of molecular biology.

A companion website offers fully searchable online text and additional USMLE-style questions for students and an image bank for faculty.

An excellent study buddy for your undergrad or medical school biochem class. The figures and succinct explanations are unrivaled, according to my more experienced friends, who used it for USMLE prep. If you are new to biochem, you'd also benefit from the excellent outlines and topic summaries in DePra & McKee's Biochemistry Study Guide Biochemistry: The Molecular Basis of Life Student Study Guide / Solutions Manual. You of course won't need the solutions sections included, but the boiled down-to-basics flow charts, equations, and mneumonics, and topic organization are a nice resource when your head is spinning or you are having trouble memorizing things.

Product Details :
Paperback: 544 pages
Publisher: Lippincott Williams & Wilkins; Fifth, North American Edition edition (July 12, 2010)
Language: English
ISBN-10: 160831412X
ISBN-13: 978-1608314126
Product Dimensions: 11 x 8.4 x 0.8 inches

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Lab Manual for General, Organic, and Biological Chemistry 2nd Edition, Karen C. Timberlake

This lab manual contains 42 experiments for the standard course sequence of topics in general, organic, and biological chemistry.

Professor Timberlake has been writing chemistry textbooks for 30 years. During that time, her name has become associated with the strategic use of pedagogical tools that promote student success in chemistry and the application of chemistry to real-life situations. More than one million students have learned chemistry using texts, laboratory manuals, and study guides written by Karen Timberlake. In addition to Basic Chemistry, she is also the author of General, Organic, and Biological Chemistry, Structures of Life, Second Edition and Chemistry: An Introduction to General, Organic, and Biological Chemistry, Ninth Edition with the accompanying Study Guide with Solutions for Selected Problems, Laboratory Manual, and Essentials Laboratory Manual.

Professor Timberlake belongs to numerous science and educational organizations including the American Chemical Society (ACS) and the National Science Teachers Association (NSTA). In 1987, she was the Western Regional Winner of Excellence in College Chemistry Teaching Award given by the Chemical Manufacturers Association. In 2004, she received the McGuffey Award in Physical Sciences by the Textbook Author Association, awarded for textbooks whose excellence has been demonstrated over time. In 2006, she also received the Texty “Textbook” Excellence Award from the Textbook Authors Association for the first edition of Basic Chemistry. She has participated in education grants for science teaching including the Los Angeles Collaborative for Teaching Excellence (LACTE) and a Title III grant at her college. She often speaks at conferences and educational meetings on the use of student-centered teaching methods in chemistry to promote the learning success of students.

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Lehninger Principles of Biochemistry 6th Edition, David L. Nelson

Lehninger Principles of Biochemistry, Fourth Edition brings clarity and coherence to an often unwieldy discipline, while incorporating the field's most important recent developments and applications.

There are several comprehensive biochemistry texts available. The fourth edition of Lehninger draws on a successful history initiated with the first edition which was a landmark text in its time. The 28 chapters follow an expected and logical progression from discussion of the fundamental molecules involved in cellular events through metabolism to the latest aspects of molecular biology. Illustrations are well done and frequent. Each chapter is accompanied by a short but useful bibliography and a set of problems. Problem answers are at the end, together with a detailed glossary and a thorough index. In an attempt to capture as broad a student audience as possible, discussions of both photosynthesis and metabolic diseases are offered. Thus, the material can be used in undergraduate/graduate courses as well as in medical school. As with other representatives of this text style, the typical student is likely to have some difficulty assigning relative importance to a given item considering the overall depth of coverage of topics. Nevertheless, careful reading with some guidance will be rewarding for most scholars and the book will serve as companion text for the usual biochemistry course. The bibliography is not as complete as some, but will provide pointers to additional material. A useful, albeit formidable (for the student) contribution.

Lehninger has the ability to present topics in a clear manner. The text reads rather smoothly and ideas are arranged in logical order. This is an excellent text for undergraduate biochemistry classes. Graduate level classes may require a more detailed presentation of material such as the text by Voet and Voet.

Product Details :
Hardcover: 1100 pages
Publisher: W.H. Freeman; Sixth Edition edition (November 21, 2012)
Language: English
ISBN-10: 1429234148
ISBN-13: 978-1429234146
Product Dimensions: 10.9 x 8.5 x 1.9 inches

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Biochemistry 4th Edition, Christopher K. Mathews

The fourth edition of Biochemistry preserves the clear writing, strong physical chemistry background, and the use of the "Tools of Biochemistry" feature to underscore the experimental nature of biochemistry. This edition has been comprehensively and consistently updated to present the current developments in a rapidly evolving field.

Christopher K. Mathews is Distinguished Professor and Chairman of the Department of Biochemistry and Biophysics at Oregon State University. Dr. Mathews was an Eleanor Roosevelt International Cancer Fellow at the Karolinska Institute in Stockholm in 1984-85 and Tage Erlander Guest Professor at Stockholm University in 1994-95. He has published several books and more than 125 scientific papers dealing with molecular virology, metabolic regulation, nucleotide enzymology, and biochemical genetics.

Product Details :
Hardcover: 1368 pages
Publisher: Prentice Hall; 4 edition (February 26, 2012)
Language: English
ISBN-10: 0138004641
ISBN-13: 978-0138004644
Product Dimensions: 10.9 x 8.6 x 1.8 inches

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Biochemistry: A Short Course 2nd Edition, John L. Tymoczko

Derived from the best-selling classic text originated by Lubert Stryer and continued by John Tymoczko and Jeremy Berg, Biochemistry: A Short Course focuses on the major topics taught in a one-semester biochemistry course. With its short chapters and relevant biological and clinical examples, this text shows biochemistry as a part of students' everyday lives. Offering the same signature writing style and physiological emphasis as the full-length text, this briefer book focuses on the major topics by eliminating details of enzyme mechanisms and organic chemistry, and by removing extraneous and advanced topics. Coverage is broken into short chapters for ease of use. Numerous examples and photos of biochemistry in action show students that biochemistry is part of everything they do and experience.

Students learn a biochemical concept, then see how that concept is applied in the real world. Clinical Insights show how our understanding of biochemical concepts influences an aspect of a disease or its cure, and Biological Insights show how simple changes in biochemical processes can have dramatic effects. The Second Edition has been fully updated with coverage of recent developments in biochemistry and human health. New Metabolism in Context sections show how new information on the role of leptins in hunger and satiety has changed the way biochemists think about obesity and diabetes. In addition to diet and obesity, other Metabolism in Context features focus on metabolism and cancer, and metabolism and exercise. The Experimental Techniques chapters (available on the companion website) have also been updated and expanded, exploring important techniques used by biochemists in the past as well as new technologies with which biochemists make discoveries in present-day laboratories.

Product Details :
Paperback: 800 pages
Publisher: W. H. Freeman; Second Edition edition (December 23, 2011)
Language: English
ISBN-10: 1429283602
ISBN-13: 978-1429283601
Product Dimensions: 10.8 x 8.5 x 1.2 inches

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Fundamentals of General, Organic, and Biological Chemistry 6th Edition, John E. McMurry

Fundamentals of General, Organic, and Biological Chemistry by McMurry, Ballantine, Hoeger, and Peterson provides background in chemistry and biochemistry with a relatable context to ensure students of all disciplines gain an appreciation of chemistry’s significance in everyday life.

Known for its clarity and concise presentation, this book balances chemical concepts with examples, drawn from students’ everyday lives and experiences, to explain the quantitative aspects of chemistry and provide deeper insight into theoretical principles. The Seventh Edition focuses on making connections between General, Organic, and Biological Chemistry through a number of new and updated features — including all-new Mastering Reactions boxes, Chemistry in Action boxes, new and revised chapter problems that strengthen the ties between major concepts in each chapter, practical applications, and much more.

Product Details :
Hardcover: 992 pages
Publisher: Prentice Hall; 6 edition (February 6, 2009)
Language: English
ISBN-10: 0136054501
ISBN-13: 978-0136054504
Product Dimensions: 8.5 x 1.3 x 10.9 inches

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Biochemistry 7th Edition, Jeremy M. Berg

In the new edition of Biochemistry, instructors will see the all the hallmark features that made this a consistent bestseller for the undergraduate biochemistry course: exceptional clarity and concision, a more biological focus, cutting-edge content, and an elegant, uncluttered design. Accomplished in both the classroom and the laboratory, coauthors Jeremy Berg and John Tymoczko draw on the field's dynamic research to illustrate its fundamental ideas.

With a balance of topic coverage and depth this updated third edition covers the subject of biochemistry, and reflects the advances made in this field since the second edition published in 1981. These advances are incorporated without loss of historical perspective and without obscuring the main goal of the text: to teach the enduring fundamentals of the discipline. Included in the third edition is a completely reorganized part one introducing the flow of information from gene to protein. It emphasizes the growing interrelatedness of molecular biology and biochemistry, and acquaints one with experimental methods of both disciplines. Also included is 150 new problems and a wealth of new material on molecular genetics and cellular processes.

Product Details :
Hardcover: 1120 pages
Publisher: W. H. Freeman; Seventh Edition edition (December 24, 2010)
Language: English
ISBN-10: 1429229365
ISBN-13: 978-1429229364
Product Dimensions: 11 x 8.7 x 1.7 inches

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Lehninger Principles of Biochemistry 5th Edition, Nelson

Lehninger Principles of Biochemistry 5th Edition, Nelson brings clarity and coherence to an often unwieldy discipline, while incorporating the field's most important recent developments and applications. This comprehensive biochemical text covers all aspects of modern biochemistry, together with many new developments since the previous edition of four years ago.

There are several comprehensive biochemistry texts available. The fourth edition of Lehninger draws on a successful history initiated with the first edition which was a landmark text in its time. The 28 chapters follow an expected and logical progression from discussion of the fundamental molecules involved in cellular events through metabolism to the latest aspects of molecular biology. Illustrations are well done and frequent. Each chapter is accompanied by a short but useful bibliography and a set of problems. Problem answers are at the end, together with a detailed glossary and a thorough index.

In an attempt to capture as broad a student audience as possible, discussions of both photosynthesis and metabolic diseases are offered. Thus, the material can be used in undergraduate/graduate courses as well as in medical school. As with other representatives of this text style, the typical student is likely to have some difficulty assigning relative importance to a given item considering the overall depth of coverage of topics. Nevertheless, careful reading with some guidance will be rewarding for most scholars and the book will serve as companion text for the usual biochemistry course. The bibliography is not as complete as some, but will provide pointers to additional material. A useful, albeit formidable (for the student) contribution.

Product Details :
Hardcover: 1100 pages
Publisher: W. H. Freeman; 5th edition (February 1, 2008)
Language: English
ISBN-10: 071677108X
ISBN-13: 978-0716771081
Product Dimensions: 11 x 8.7 x 1.7 inches

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